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Ali Mirazimi, Associate Professor (Docent)
Phone: +4684572573
Email: Ali.Mirazimi@smi.se

Karolinska Institutet



Research summary:
Andersson, I., Bladh, L., Mousavi-Jazi, M., Magnusson,K-E. Lundkvist, Å., Haller, O. and Mirazimi, A. (2004). Human MxA protein inhibits the replication of Crimean Congo hemorrhagic fever virus (CCHFV). J Virol. 2004 Apr;78(8):4323-9.

Åkerström, S., Mousavi-Jazi, M., Klingström, J.,Leijon, M., Lundkvist, Å. and Mirazimi A. (2005). Nitric oxide inhibits the replication cycle of severe acute respiratory syndrome (SARS) Coronavirus. J Virol. 2005 Feb;79(3):1966-9

Andersson, I., Lundkvist, Å., Haller,O. and Mirazimi, A. (2006).Type I Interferon inhibits Crimean-Congo Hemorrhagic Fever Virus (CCHFV) by inducing MxA protein in human target cells . Accepted J. Med. Virol 2006.

Andersson, I, Simon, M., Lundkvist, Å., Nilsson, M., Holmström, A., Elgh, F. and Mirazimi A. (2004). The role of actin filaments in targeting of Crimean Congo hemorrhagic fever (CCHF) virus nucleocapsid protein to perinuclear regions of mammalian J Med Virol. 2004 Jan;72(1):83-93.




Methods:
Crimean Cingo hemorraghic fever virus
P4-lab
Interferons
MxA


Research projects:
The role of innate inmmunity for controlling CCHFv infection
The effect of CCHFv infection on epitelial and endothelial barriers
The role of Nitric oxide in SARS virus replication cycle
Immune responses and pathogenesis of hantavirus infections
The role of Innate immunity for controlling the crimean congo hemorraghic fever virus


Groups:
Ali Mirazimi

Areas:
Members of Infection
Members of KiiM